[JuveLook] Awakening Collagen in Your Skin

Kkeuthan Clinic's Skin Booster Layering Treatment Method

*1. Pre-Treatment Stage

- Cooling or anesthetic cream is applied depending on the treatment area.

Kkeuthan Clinic's 4-Step Skin Booster Layering Process

*2. 4-Step Skin Booster Layering (Utilizing MTS or Potenza RF treatments)

Step 1: Skin Booster Ampoule Application

- This is a priming process to evenly apply a thin layer over the entire skin surface, preparing for the next stage.

- The purpose of this is to elicit a natural response from the epidermal layer.

Step 2: Skin Booster Ampoule Application

- After light needling on the epidermal layer, the ampoule is applied once more.

Step 3: Skin Booster Ampoule Application

- Needling is performed, focusing on the basement membrane, which is the boundary between the dermis and epidermis, and the ampoule is then applied over it.

Step 4: Skin Booster Ampoule Application

- For areas requiring special care, such as pores and scars, precise needling is performed, followed by concentrated ampoule application.

*3. Post-Treatment Soothing Stage

- After the treatment, a Jaungo modeling mask is applied to comfortably soothe the skin.

At Kkeuthan Clinic, during skin booster treatments, the medication is layered a total of four times within a single treatment session to ensure broader and more even delivery to the skin.

The skin booster layering process can help reduce treatment discomforts such as bruising, swelling, medication injection errors, and hypersensitivity reactions. We recommend deciding whether to proceed with this treatment after a thorough consultation with a specialist.

Kkeuthan Clinic's Layering Technique: Skin Booster Absorption Method

JuveLook formulations have the characteristic that they are difficult to be sufficiently absorbed into deeper layers by simply applying them to the skin surface.

Therefore, Kkeuthan Clinic utilizes MTS (Microneedle Therapy System) and Potenza RF (microneedle radiofrequency) devices to apply the layering absorption technique for skin boosters.

JuveLook skin boosters have a particle size of approximately 30-50μm. When using MTS or Potenza RF devices, a sufficient amount of drug absorption can be expected. Specifically, the layering technique is applied to reduce potential loss during drug application and ensure uniform delivery.

MTS Layering

MTS creates micro-channels of approximately 150μm on the skin surface. This serves to open pathways for the skin booster to be effectively absorbed into the skin.

Our Kkeuthan Clinic focuses on enhancing drug absorption rates through a 4-step layering method utilizing MTS.

Step 1: Application for Epidermal Layer Priming

Step 2: Light Needling on Epidermal Layer followed by Application

Step 3: Application on Dermal-Epidermal Junction

Step 4: Concentrated Application on Specific Concern Areas like Pores and Scars

After all layering processes are complete, the treatment concludes with skin soothing care using a Jaungo modeling mask. This can help reduce the burden of inflammatory reactions after the procedure.

Potenza RF (Microneedle Radiofrequency) Layering

Potenza RF creates micro-channels of approximately 180μm in the skin. By utilizing radiofrequency heat to contract these channels, it helps reduce potential fluid backflow (overflow) that can occur during typical needle procedures. In this way, we expect precise delivery of JuveLook to the dermal layer without medication loss.

While there might be a possibility of medication loss compared to manual injection methods, Potenza RF has the advantage of delivering the medication more uniformly to the targeted dermal layer. Furthermore, it helps reduce the burden of pain during the procedure and promotes even absorption of the medication.

Similar to MTS treatment, needle depth can be adjusted. This also proceeds with a 4-step layering technique.

Kkeuthan Clinic can select the appropriate treatment method between MTS and Potenza RF, or combine both, depending on the individual's skin condition and improvement goals.

Reasons Why Kkeuthan Clinic Applies This Method

JuveLook is prepared by mixing its powdered formulation with saline solution just before treatment.

At this time, sufficient hydration with saline is crucial, as it is essential to ensure the stable viscosity of the medication.

If treated with a manual injection method, there is a risk of nodules forming if the medication is not sufficiently hydrated or if the injection depth is not appropriate, leading to medication concentrated in one area.

It should also be considered that if the medication enters the subcutaneous fat layer instead of the desired dermal layer, it may be difficult to achieve the expected results from the treatment.

Even with the utmost care taken during the dilution process of drugs for injection procedures, it is challenging to completely eliminate the possibility of nodule formation within the skin. Considering this, we carefully determine our treatment methods to prioritize safety while delivering satisfying results.

At our medical institution, we apply a layering technique that meticulously adjusts various stages, from controlling the dilution concentration and viscosity of the medication to creating micro-channels and determining the absorption method into the skin. We tailor treatment plans to each individual's skin condition, helping active ingredients to be effectively delivered deep into the skin.

We believe that pursuing the full effectiveness of treatments while minimizing risks for our patients is the right approach.

What is Juvelook Skinbooster?

Juvelook is a new concept skin booster where PDLLA (Poly-D,L-lactic acid) and hyaluronic acid (HA) work together.

This treatment can positively influence the improvement of skin texture, enlarged pores, fine lines, and acne scars. In particular, it is expected to have a regenerative effect by stimulating the natural production of collagen and elastin in the dermis, generally increasing skin elasticity and density.

PDLLA is designed with finer particle sizes than existing PLLA (e.g., Sculptra). Thanks to this characteristic, it has good penetration into the skin and can help reduce the possibility of side effects such as nodule formation or inflammatory reactions. Therefore, individuals with sensitive skin can also consider this treatment.

The main components of Juvelook are as follows:

PDLLA 42.5mg (a substance that induces natural collagen production)

Non-crosslinked Hyaluronic Acid 7.5mg (contributes to skin hydration and improvement of the protective barrier)

When PDLLA enters the dermis, it promotes the activity of fibroblasts, inducing the production of collagen and elastin fibers.

Collagen determines skin density and volume, while elastin is a key component responsible for skin elasticity.

When these two fibers increase harmoniously, it can help fundamentally improve various skin concerns such as fine lines, enlarged pores, and decreased skin elasticity.

Furthermore, PDLLA can also stimulate stem cells to differentiate into new fibroblasts.

Through this process, aged skin cell structures are refreshed, and a remodeling effect that rebuilds the skin's inherent structure can be expected.

Fibroblasts, which produce collagen and elastin in the skin, decline in function with age, and the frequency of new cell generation also decreases.

Beyond simply stimulating existing fibroblasts, Juvelook Skinbooster also participates in the formation of new fibroblasts, thereby more actively promoting the long-term production of collagen and elastin fibers.

Recommended for

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• 01. Individuals concerned about decreased skin elasticity and enlarged pores
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• 02. Individuals bothered by noticeable pores or acne scars
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• 03. Individuals desiring natural volume improvement without exaggeration
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• 04. Individuals concerned about uneven skin texture and fine wrinkles
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• 05. Individuals who desire the effect of natural collagen regeneration but feel apprehensive about injection procedures
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• 06. Individuals expecting healthy and natural skin firmness and lifting effects
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What is the Clinical Basis for Juvelook?

The regenerative effect of PDLLA on the dermis has been proven numerous times through various academic studies.

Kwon et al., Dermatologic Surgery, 2022 paper: As a result of three treatments with PDLLA skin booster at 4-week intervals, increased skin thickness and dermal density were reported, along with improved skin elasticity.

Kim et al., Journal of Cosmetic Dermatology, 2021 paper: It was revealed that PDLLA induces not only collagen but also elastin production. This demonstrates a broader fiber regeneration effect compared to typical collagen-focused products.

Han et al., Lasers in Surgery and Medicine, 2020 paper: When applied to acne scar patients, it was confirmed that an MTS-based absorption method efficiently delivers the drug to the dermis, reducing epidermal irritation and side effects.

Director's Treatment Philosophy

Among those who visit our medical institution for the first time, many come with deep concerns over what might seem like a minor skin texture issue.

For instance, concerns such as noticeable pores, rough skin texture, or makeup not applying smoothly.

While others might not even notice, for the individual, this can be a significant psychological burden.

We would like to recommend Juvelook treatment to those with such concerns.

This is because Juvelook not only helps to smooth skin texture and refine pores but also supports the skin in regaining its natural healthy resilience.

If you usually worry about pain during injection procedures or are concerned that the medication might not be effectively delivered,

you might want to consider experiencing Juvelook Skinbooster treatment, which applies our medical institution's layering technique.

Benefits of the Treatment

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• 01. The combination of FDA-approved high molecular weight PLA and hyaluronic acid is expected to improve various problematic skin conditions.
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• 02. It induces natural collagen production, helping to achieve more natural results over time.
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• It can improve skin elasticity and contribute to refining overall skin texture. It can also be expected to alleviate fine wrinkles or scars left by acne.
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• The substance used in this procedure naturally breaks down and is absorbed within the human body. It is designed not to leave any residues in the body over time.
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