[PN Regeneration Care] for Damaged Skin Environment

Features of Endran Healer

1. A Reasonable Choice with Equivalent Ingredients

Endran Healer uses polynucleotide (PN) ingredients derived from salmon. This can help reduce the financial burden of the procedure.

2. Customized Treatment Plan Considering Your Skin

By thoroughly analyzing the skin structure, PN ingredients are injected into the appropriate skin layer and depth. This method focuses on enhancing the effectiveness of the treatment.

3. Verification of Drug Injection via Embo Reaction

Immediately after the procedure, we visually confirm with the patient whether an embo reaction occurs. This is a process to check if the drug has been properly injected into the intended area.

4. Consultation and Treatment Led by Medical Professionals

Medical professionals thoroughly assess each patient's skin condition and treatment experience. Based on this, we develop a personalized treatment plan suitable for you.

5. Support for Skin Irritation Relief and Rapid Recovery

After the procedure, we use a Jaungo modeling pack to help soothe the skin. This supports even sensitive skin to undergo the recovery process more comfortably.

6. Embo Spacing Adjustment Considering Skin Characteristics of Each Area

Considering the differing skin characteristics of each facial area, embo spacing is delicately adjusted. For instance, cheeks and forehead maintain appropriate spacing, while sensitive areas like the eye and mouth areas are injected more precisely. This approach comprehensively considers the skin thickness, elasticity, and wrinkle direction of each area.

Reasons to Consider Endran Healer

1. A Reasonable Choice Offered with Equivalent Ingredients

As the patent period for polynucleotide (PN) ingredients has expired, various treatments using PN extracted from salmon are entering the market.

Endran Healer also consists of these PN ingredients.

This offers patients the opportunity to experience the treatment at a more realistic cost.

Therefore, if you wish to maintain functionality while reducing the financial burden of the procedure,

we suggest Endran Healer as a worthwhile option to consider.

2. Treatment Process as Important as Ingredients

It is difficult to expect the same treatment results for everyone with PN ingredients alone.

Endran Healer treatment goes beyond simply injecting the drug into the skin.

The injection is performed with meticulous consideration of the exact skin layer, depth, and appropriate amount.

It is crucial to delicately adjust the injection depth according to various individual patient characteristics such as skin thickness, degree of damage, and pore type.

This approach has the potential to more effectively induce dermal remodeling and collagen regeneration.

3. Checking Injection Area via Embo Reaction

During the procedure, whether the PN drug has reached the target area effectively

is visually confirmed by both the medical staff and the patient.

The embo reaction can be considered an indicator that the drug has been accurately injected into the desired area.

Therefore, immediately after the procedure, we take time to check for the presence or absence of the embo reaction with the patient.

This embo verification process is conducted based on the judgment that it can provide meaningful information from the early stages of the treatment.

4. One-on-One Customized Consultation and Treatment Directly Performed by Medical Professionals

Medical professionals go beyond simply explaining the procedure; they conduct in-depth consultations directly with each individual patient.

Various factors such as the patient's current skin condition, degree of sensitivity, previous treatment experiences, and types of cosmetics being used

are meticulously diagnosed directly by the medical team throughout the entire procedure.

This precise diagnosis serves as the foundation to help PN ingredients work more effectively on the skin.

Furthermore, we anticipate potential discomfort or side effects that may occur and prepare to manage them appropriately.

5. Post-Procedure Skin Soothing and Recovery Support

After PN treatment, a Jaungo modeling pack is used to help soothe the skin and aid in the recovery process.

엔드란 힐러를 고려하는 이유

1. 동등한 성분으로 제시되는 합리적인 선택

폴리뉴클레오티드(PN) 성분의 특허 기간이 만료되면서, 연어에서 추출한 PN을 사용한 여러 시술이 시장에 나오고 있습니다.

엔드란 힐러도 이러한 PN 성분으로 이루어져 있습니다.

이는 환자분들께 더 현실적인 비용으로 시술을 경험할 기회를 제공해드립니다.

따라서 기능성을 유지하면서도 시술 비용에 대한 부담을 덜고 싶은 분들이 계시다면,

엔드란 힐러를 고려해볼 만한 선택지로 제안해드립니다.

2. 성분만큼 중요한 시술 과정

PN 성분만으로는 모든 사람에게 동일한 시술 결과를 기대하기는 어렵습니다.

엔드란 힐러 시술은 단순히 약물을 피부에 넣는 것을 넘어섭니다.

피부의 정확한 층과 깊이, 그리고 적절한 양을 면밀히 고려하여 주입을 실시합니다.

환자 개인의 피부 두께, 손상된 정도, 모공의 형태 등 다양한 특성에 맞추어 주입 깊이를 섬세하게 조절하는 것이 중요합니다.

이러한 접근을 통해 진피 리모델링 및 콜라겐 재생을 더 효과적으로 유도할 가능성이 있습니다.

3. 엠보를 통한 주입 부위 점검

시술 시 PN 약물이 목표 부위에 잘 도달했는지 여부를

의료진과 환자가 함께 육안으로 확인하는 과정을 가집니다.

엠보 현상은 약물이 원하는 부위에 정확히 주입되었음을 나타내는 지표로 여겨질 수 있습니다.

따라서 시술 직후 환자분과 함께 엠보 현상의 유무를 확인하는 시간을 갖습니다.

이러한 엠보 확인 과정은 시술의 초기 단계에서부터 유의미한 정보를 제공할 수 있다는 판단 아래 진행됩니다.

4. 의료진이 직접 진행하는 일대일 맞춤 상담 및 시술

의료진은 단순히 시술을 설명하는 것을 넘어, 환자 개개인과 심층적인 상담을 직접 진행합니다.

환자의 현재 피부 상태, 민감성 정도, 이전 시술 경험, 사용 중인 화장품 종류 등 다양한 요소를

의료진이 시술 전반에 걸쳐 직접 세밀하게 진단합니다.

이러한 정밀 진단은 PN 성분이 피부에 보다 유효하게 작용할 수 있도록 돕는 기반이 됩니다.

또한 발생할 수 있는 불편감이나 부작용의 가능성을 미리 예측하고 적절히 관리할 수 있도록 대비합니다.

5. 시술 후 피부 진정 및 회복 과정 지원

PN 시술 후에는 자운고 모델링팩을 사용하여 피부 진정과 회복 과정에 도움을 제공합니다.

We provide complex traditional Korean calming care that quickly stabilizes heat, redness, and sensitive reactions occurring on the skin.

This process can help reduce the burden on the skin by preemptively regulating its excessive immune response.

Thanks to this, even those with thin or sensitive skin can undergo PN procedures a little more comfortably.

Our clinic emphasizes an integrated approach that meticulously manages even the recovery process after treatment.

6. Customized Emboss Interval Design Considering Treatment Area Characteristics

When performing EndranHealer treatment, we carefully plan the injection intervals not only for the injection site but also according to the patient's skin characteristics.

For example, in areas where the dermis is relatively thick and the area is wide, such as the cheeks or forehead,

the PN component can spread widely from a single point, so injecting at intervals of about 1 to 1.5 cm can still yield sufficiently good results.

However, in areas with thin skin tissue and many fine wrinkles, such as around the eyes or mouth,

injecting more densely at 0.5 cm intervals can be more effective for refining skin texture.

If the overall skin is thin and has many sunken areas, or

if the skin texture structure has become irregular due to previous laser treatments, we may consider injecting PN more finely into the cheek or forehead areas as well.

After closely analyzing the patient's skin thickness, elasticity, wrinkle direction, and the main goals desired through the treatment,

we design customized emboss injection positions and intervals for each individual.

Even when using the same amount of PN, this individualized treatment method can make a significant difference in the expected results.

This personalized treatment method is one of the characteristics of EndranHealer.

What changes can be expected with EndranHealer?

1. It can help promote collagen and elastin production, contributing to thicker and firmer skin.

The PN (Polynucleotide) component extracted from salmon induces the activation of fibroblasts in the skin's dermis,

which positively influences the process of collagen and elastin production.

Through this, an increase in skin thickness, reduction of fine wrinkles, and overall elasticity restoration can be expected.

Furthermore, pore improvement effects can also be considered.

2. It helps restore damaged skin barriers and build the skin's natural healthy strength.

PN promotes the secretion of various growth factors such as TGF and FGF, aiding epidermal cell regeneration and contributing to the restoration of skin barrier function.

As a result, it can help reduce inner skin dryness, calm sensitive skin, and improve the skin's inherent regenerative capacity.

In particular, it can have a positive impact on the stabilization and regeneration process of skin that has become sensitive after laser or peeling treatments.

3. Skin Changes Experienced Through Natural Improvement

EndranHealer is not a procedure that creates immediate volume like fillers or directly controls muscle movement like Botox.

Instead, by activating the skin's healthy functions, you can experience softer skin texture, reduced dryness, and a feeling that makeup applies better.

If you desire naturally improved skin condition rather than drastic changes, considering EndranHealer is recommended.

Mechanism of Action of EndranHealer

1. Activates fibroblasts to support a healthy skin structure.

The main component of EndranHealer, PN (Polynucleotide), is

a high-purity DNA fragment extracted and purified from salmon. When this component is injected into the skin,

it acts like a recovery signal sent to damaged tissue, contributing to the stimulation and activation of fibroblasts.

These fibroblasts play a role in producing key skin components such as collagen, elastin, and hyaluronic acid,

and consequently can play an important role in forming a firmer and healthier skin structure.

2. Promotes the skin's self-regenerative power through growth factor secretion.

Activated fibroblasts are known to secrete various types of growth factors.

Among them, TGF-β is a representative growth factor that aids collagen synthesis.

FGF is known as a growth factor that aids in the skin's regenerative capabilities and recovery processes.

VEGF can help promote smooth microcirculation within the skin.

These growth factors contribute to creating a healthy skin regeneration environment.

They play a role in supporting the skin's epidermis and protective barrier to recover on their own.

As a result, it can help reduce skin sensitivity, improve inner dryness, and enhance overall recovery.

3. Due to improved dermal density, you may experience a feeling of firmer, more plump skin.

Endran Filler is a treatment that acts on the dermis, the skin's core component.

PN contributes to the reconstruction of extracellular matrix (ECM) components such as collagen, elastin, and hyaluronic acid, which make up the dermal layer.

This helps important components like collagen, hyaluronic acid, and proteins to more densely fill the dermal tissue.

As a result, internal skin density becomes firmer, and improvement in sunken areas is expected. Additionally, skin texture can be refined, contributing to better makeup adherence.

4. Anti-inflammatory effects that reduce skin irritation and promote faster recovery can also be expected.

In addition to aiding skin regeneration, PN can also play a role in regulating subtle inflammatory responses within the skin.

Chronic redness

Skin that reacts sensitively to external stimuli

Sensitive reactions appearing after laser procedures

In such cases, it can also help reduce skin inflammatory reactions while aiding the recovery process.

Therefore, Endran Filler is a PN treatment worth considering even for those with relatively sensitive skin.

Endran Filler Treatment Process

1. Skin Condition Assessment and Diagnosis

By thoroughly analyzing the patient's skin thickness, elasticity, and sensitivity,

this information is used to plan the appropriate depth and method for PN injection.

2. 1:1 In-depth Consultation with a Specialist

The specialist directly diagnoses the areas requiring improvement and the scope of the treatment,

and establishes the treatment plan.

A customized treatment plan is prepared, considering each individual's skin characteristics, rather than a standardized approach.

3. Anesthetic Cream Application

Since PN formulation is directly injected into the dermal layer of the skin,

a sufficient anesthesia time of about 20 to 30 minutes is provided before the treatment.

This is to help minimize any discomfort that may occur during the procedure.

4. Endran Filler Injection Procedure

PN is precisely injected according to the pre-planned depth and location.

The injection site is immediately confirmed by the resulting 'embossing' effect after injection,

and if necessary, adjustments are made on-site to ensure treatment accuracy.

5. Soothing Care with Jaungo Modeling Pack

Immediately after the procedure, a Jaungo modeling pack is used to

quickly alleviate reactions such as injection marks, redness, and warmth.

This helps reduce excessive immune responses and assists in the safe recovery process of the skin.

Recommended Endran Filler Treatment Cycle and Duration of Effects

1. Initial Intensive Management Treatment (Recommended 3 sessions)

Generally, we recommend undergoing a total of 3 sessions at 1-month intervals.

There are several reasons why this process is necessary.

For the treatment to be effective, it is important that polynucleotide (PN) components are properly settled in the dermal layer of the skin.

Only when a sufficient amount of PN reaches the dermal layer can fibroblasts be activated.

This stimulation of fibroblasts can positively impact the improvement of collagen structure, helping the skin to transform healthily.

2. Retouch for maintaining treatment effects

If you wish to maintain the satisfactory changes after the treatment for a longer period,

you may consider receiving additional treatments approximately every 6 months to 1 year.

Of course, the duration of treatment effects may vary depending on individual skin condition and lifestyle patterns.

Generally, after completing the basic 3-session course, the effects are expected to last for about 6 to 12 months.

3. How long do the changes after treatment last?

After the collagen regeneration process is complete,

positive effects on skin texture, elasticity, and density improvement can typically last for over 6 months.

However, in some situations, the duration of treatment effects may be somewhat reduced.

If the skin is exceptionally thin or already highly damaged

If there are lifestyle habits detrimental to skin health, such as smoking or excessive UV exposure

4. When will changes from the treatment appear?

Immediately after the procedure, slight embossing or mild swelling may be observed at the drug injection site.

After about 1 week, you may feel that makeup applies better than before, or experience a smoother skin texture.

At the 2-3 week mark, improved skin elasticity and increased density, along with a reduction in fine wrinkles, can be expected.

Upon completing all 3 treatment sessions, you can directly feel positive changes in your skin's internal structure and experience overall skin condition improvement.

Endran Hiller, how much pain should I expect?

You may feel a stinging sensation during the procedure.

Since the drug is injected directly into the dermal layer, complete absence of pain is not possible. However, the procedure is performed after sufficient anesthesia, so most patients tend to tolerate it well.

Most individuals complete the procedure without significant discomfort.

Degree of pain felt by area

Areas like the cheeks, forehead, and around the mouth are less likely to experience significant pain.

Sensitive areas such as around the eyes, bridge of the nose, and chin may temporarily experience a stinging sensation.

For areas with larger pores, a slightly heavy pressure may accompany the injection.

Methods to alleviate pain

Anesthetic cream is applied before the procedure, and sufficient time is allowed for it to take full effect.

The drug is injected delicately in small, divided amounts to minimize pain.

The patient's pain response is continuously monitored and adjusted during the procedure.

After the procedure, we carefully attend to the finishing touches, including pack management to help soothe the skin.

Endran Hiller Treatment: Consider if you are one of these individuals

1. Those who are starting to notice prominent fine wrinkles on their face

Especially if you are concerned about fine wrinkles spreading densely around your eyes, cheeks, and mouth,

this could be an option for those who feel burdened by lifting or filler procedures but desire natural wrinkle improvement.

2. Those with sensitive skin that tends to redden easily

This may include individuals who react sensitively to cosmetic changes, or who have skin that easily reddens and shows flushing.

If you wish to restore a damaged skin barrier to health, this procedure may be helpful.

3. When inner skin dryness and makeup caking feel uncomfortable

This refers to a condition where the skin feels oily on the surface but dry and tight underneath, and makeup tends to cake easily.

It can be beneficial for dehydrated skin that is difficult to improve with typical moisturizing care alone.

4. When skin has become sensitive due to frequent treatments

This may apply to cases where the skin becomes thinner or reacts sensitively after repeated procedures such as laser or peeling treatments.

It can be a viable alternative to consider when you wish to restore your skin's natural health and vitality.

5. For those who desire improved skin density and overall skin texture refinement

This describes a condition where the skin feels loose and saggy due to a loss of elasticity.

Improvements can be expected for those concerned about blurred contours in the cheekbone and cheek areas, and uneven skin texture.

Embossing Reaction That May Occur After Endranh Filler Treatment

Occasionally, small areas of embossing (slight bumps) may appear on the skin surface after Endranh Filler treatment.

This can be interpreted as a sign that the injected treatment solution has reached the dermal layer effectively.

It is a normal reaction for the skin to temporarily show slight bumps, and it is an indication of the treatment's expected effect.

Most embossing naturally subsides within 1-2 days after the treatment.

For those with thin or dry skin, it may last 2-3 days, and for sensitive areas like around the eyes or mouth, it could persist for up to 4 days.

In very rare cases, embossing may persist for 5-7 days or more, but

if there are no unusual symptoms such as pain, heat, or severe redness, you do not need to be overly concerned.

On the contrary, it could be a positive sign that the treatment solution is being absorbed slowly and working on the skin for a longer period.

Post-Treatment Precautions

• ✔ Bumps, redness, and mild pain in the treated area typically last about 2-3 days.
• ✔ Bruising, needle marks, and swelling may persist for about 1-2 weeks after the treatment.
• ✔ It is advisable to refrain from alcohol, smoking, saunas, swimming pools, and strenuous exercise for 7 days to avoid the risk of skin irritation.
• ✔ After the procedure, pay attention to moisturizing care to soothe the skin. Additionally, it is important to apply sunscreen diligently when going outdoors.